South Carolina Midlands Vacation Packages
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to CA $4,200 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Your South Carolina Midlands Vacation
Whether you're heading to South Carolina Midlands for its rich history, spectacular views or something else entirely, this destination is one you won't forget in a hurry. Create your ultimate break with one of our South Carolina Midlands vacation packages. With so much to see and do on a trip to South Carolina Midlands, it can be difficult to know where to start. Kick off your travels in Columbia at Riverbanks Zoo and Garden and Williams Brice Stadium — two popular attractions here. Another city worthy of a spot on your itinerary is Florence. Don't miss Magnolia Mall and Mcleod Regional Medical Centre. Expedia has flights, hotels, car rentals and more to help you create your very own customized South Carolina Midlands vacation today.
Top South Carolina Midlands Vacation Deals
Price found within the past 48 hours. Click for updated prices.
North Beach Resort & Villas
Windy Hill
CA $1,610
per person
Sep 20 - Sep 27
found 3 hours ago
Roundtrip non-stop flight included
Buffalo (BUF) to Myrtle Beach (MYR)
8.8/10 Excellent! (1,044 reviews)
Staff members were helping as needed. The property needs to be repaired/ maintained. The room had broken bed, uncomfortable mattress and worn out couch and chairs. Closet and bathroom were not cleaned (found hairs……). Great kitchen and nice space at all. The staff members helped us in fixing the bed and the mattress. The other odd thing is that I booked via Expedia a one bedroom with two beds ( one for us, and separate bed to our child), but they gave us a room with a single bed inside ( not a big deal, but our child was not happy with it)
Reviewed on Aug 11, 2026
Marina Inn Grande Dunes Condos & Suites
CA $1,328
per person
Nov 1 - Nov 8
found 4 hours ago
Roundtrip non-stop flight included
Toronto (YTO) to Myrtle Beach (MYR)
9.4/10 Exceptional! (178 reviews)
Rooms and bathrooms were dirty. Carpet smelled like urine. Couches had stains. Not worth the price. Unit needs renovation. Old furniture. We didn't even get housekeeping. Our housekeeping service was skipped. Lady did not understand English. We asked her to come back later and she never showed up.
Reviewed on Aug 10, 2026
Sands Beach Club
CA $1,051
per person
Sep 20 - Sep 27
found 1 day ago
Roundtrip non-stop flight included
Buffalo (BUF) to Myrtle Beach (MYR)
8.8/10 Excellent! (125 reviews)
Great location had a really good time. Good rooms just very inconvenient. Having to switch in the middle of our stay wasn’t notified before hand.
Reviewed on Aug 3, 2026
Where to stay in South Carolina Midlands
Find the best South Carolina Midlands areas and neighborhoods for the activities you enjoy most. Learn more about South Carolina Midlands
Downtown Columbia
3 out of top 10 points of interest in this area
Travelers come to Downtown Columbia for its lively bars, and you can see top attractions like South Carolina State House and Columbia Museum of Art while you're in town.
The Vista
The Vista is popular for its abundant dining options, and if you're looking for more to see and do, you might think about a trip to Colonial Life Arena or Koger Center for the Arts.
Tega Cay
Discover a picturesque peninsula with a 27-hole golf course, croquet court, lighted tennis and pickleball courts, walking trails, and 13 city-owned parks. Enjoy the hilly, densely forested terrain and abundant wildlife.
Rosewood
If you're looking for some top things to see and do in Rosewood and surrounding area, you can visit South Carolina State Fairgrounds and Williams Brice Stadium.
Eau Claire
Travelers like the parks in Eau Claire, and Three Rivers Greenway is a top attraction you might want to visit.
Ready to book your vacation to South Carolina Midlands?
South Carolina Midlands Hotel Deals
Hilton Garden Inn Columbia/Harbison
434 Columbiana Dr Columbia SC
Fully refundableReserve now, pay when you stay
CA $119
CA $133 total
Aug 23 - Aug 24
includes taxes & fees
9/10 Wonderful! (2,247 reviews)
"."
Reviewed on Aug 11, 2026
Quality Inn & Suites Florence Civic Center
150 Dunbarton Dr Florence SC
Fully refundableReserve now, pay when you stay
CA $123
CA $138 total
Aug 17 - Aug 18
includes taxes & fees
La Quinta Inn by Wyndham Columbia SE / Fort Jackson
7333 Garners Ferry Rd Columbia SC
Fully refundableReserve now, pay when you stay
CA $142
CA $159 total
Aug 24 - Aug 25
includes taxes & fees
8.2/10 Very good! (1,024 reviews)
"Wes"
Reviewed on Aug 10, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular South Carolina Midlands attractions
Carowinds Theme Park
8.8/10 (962 reviews)
Choose from 13 roller coasters, chase your friends in a bumper car, enjoy the water slides and beaches of Boomerang Bay, and walk with dinosaurs.
University of South Carolina
9.0/10 (2,467 reviews)
Walk around the campus of University of South Carolina, a top university in Columbia. Experience the area's acclaimed theater scene or attend a sporting event.
Riverbanks Zoo and Garden
8.8/10 (1,195 reviews)
Why not meet the animals who call Riverbanks Zoo and Garden home during your trip to Columbia? You can attend a sporting event while in the area.
Williams Brice Stadium
8.8/10 (938 reviews)
Catch an event at Williams Brice Stadium during your trip to Columbia. You can attend a sporting event while in the area.
Columbia Metropolitan Convention Center
8.4/10 (594 reviews)
Learn about the events happening at Columbia Metropolitan Convention Center during your trip to Columbia. Experience the area's acclaimed theater scene or attend a sporting event.
Colonial Life Arena
8.8/10 (1,029 reviews)
Catch an event at Colonial Life Arena during your trip to Columbia. Experience the area's acclaimed theater scene or attend a sporting event.
Rock Hill Sports & Event Center
9.2/10 (192 reviews)
Catch an event at Rock Hill Sports & Event Center during your trip to Rock Hill.
What to do in South Carolina Midlands
Frequently asked questions
How much does a South Carolina Midlands vacation package cost?
From as little as CA $947. Yes, you read that correctly. Our South Carolina Midlands vacation packages are the easiest way to stretch your budget further. Bundle your preferred hotels, flights and rental car and get out and see this vibrant destination.
How do I get a cheap travel package to South Carolina Midlands?
Track down flights that suit your schedule, add a hotel to your booking and see how much you save with a South Carolina Midlands vacation package. It's that simple! From flights and hotels to tours and rental cars, Expedia makes traveling cheap and easy. And with over 550 airlines and 1,000,000 hotels throughout the world to select from, you won't be short of choice.
Where should I stay in South Carolina Midlands?
If you're eager to explore University of South Carolina and South Carolina State House, the city of Columbia is the destination for you.
What are the top hotels in South Carolina Midlands?
Take a look at Country Inn & Suites by Radisson, Columbia, SC and Graduate Columbia, S.C.. They're top picks for many travelers to Columbia. If North Augusta features in your travel plans, Holiday Inn Express & Suites Aiken, an IHG Hotel and Fairfield Inn & Suites by Marriott Aiken are both welcoming options.
How far in advance should I book my South Carolina Midlands vacation?
Reward yourself with the widest variety and the lowest prices by booking your South Carolina Midlands adventure nice and early. Air carriers usually publish tickets around 12 months before departure, so start your planning ASAP. Having said that, Expedia is constantly working to give you the best bargains around, so it's always a good time to book your dream vacation!
What does an Expedia South Carolina Midlands travel package include?
Car rentals, flights and hotels — we bring you the best deals. All you'll have to do is pick and choose your ideal combination. After you've made your booking, you can add on the exciting stuff like activities and tours. Our travel packages make it simple to craft an exciting South Carolina Midlands escape.
What should I know before booking a South Carolina Midlands travel package?
Locking in all the parts of your vacation together is an excellent way to save. Bundle car rentals, airfares and hotels into a handy little package. But it's not just hotels. Expedia features all types of properties, including vacation rentals such as mountain cabins and city apartments. Your choices are almost endless!
Can I choose my airline with a South Carolina Midlands Expedia vacation package?
Expedia has access to more than 550 airline partners worldwide, so you sure can! Just select your preferred air carrier and put together your ideal South Carolina Midlands vacation.
If I'm not able to travel, can I cancel my South Carolina Midlands vacation package?
Yes, you can. We realize life happens, so we're here to help if you have to make changes to your South Carolina Midlands vacation package. You may be able to change or cancel your itinerary at no cost if you've booked within 24 hours. Your airline, hotel or car rental company may impose a fee if you booked more than 24 hours ago. Take a look at our Customer Service Portal for further information. Also, check your itinerary for the nitty-gritty on change fees.
Explore a world of travel with Expedia
- Cheap Hotels in South Carolina
- Lyon Street Hotels
- Beach Hotel Hotels in South Carolina
- 'The Rosewood House' 3 Mi to Downtown Columbia!
- Guest Houses in Cedar Creek
- Rv Parks in South Carolina
- Wyndham Garden Columbia/Ft. Jackson
- Oceanfront Hotels in South Carolina
- Comfort Inn Blythewood
- B&B in South Carolina
- La Quinta Inn by Wyndham Columbia NE/Fort Jackson
- Mainstay Suites Columbia Harbison
- Luxury Hotels in Columbia
- Ski Hotels in South Carolina
- South Carolina Hotels
- Hostels in Columbia
- Vacation Homes in Columbia
- Condo Rentals in South Carolina
- Hotels near Fort Jackson
- Home2 Suites by Hilton Blythewood
- Cabin Rentals in South Carolina Midlands
- Days Inn by Wyndham Blythewood North Columbia
- Cheap Hotels in Columbia
- Columbia Hotels
- Hotels near University of South Carolina
- Honeymoon Resorts and in South Carolina
- Blythewood Hotels
- Motels in Columbia
- Forest Acres 5BR Home w/ Private Pool & Pool House
- Updated Five Points Condo ~ Half
- Cabin Rentals in South Carolina
- Lgbt Friendly Hotels in Killian
- Hotels near William Jennings Bryan Dorn Veterans Affairs Medical Center
- Lake Hotels in South Carolina
- Dentsville Hotels
- Pet-Friendly Hotels in South Carolina
- Casino Hotels in South Carolina
- Hotels with Balconies in Columbia
- Hotels with Free Airport Shuttle in Columbia
- 5 Star Hotels in Columbia
- Golf Hotels in South Carolina
- Villas in South Carolina
- Springhill Suites by Marriott Columbia near Fort Jackson
- Houseboats in South Carolina
- Adults Only Resorts & in Columbia
- All Inclusive Resorts and in South Carolina
- Luxury Hotels in South Carolina
- Casino Hotels in Blythewood
- Adults Only Resorts & in South Carolina
- B&B in Woodfield
- Hotels with an Indoor Pool in Columbia
- Downtown Farm Charm
- Downtown Columbia Hotels
- Spa Hotels in South Carolina
- Sleep Inn Columbia
- Family Hotels in South Carolina
- Hotels near Sesquicentennial State Park
- Shandon Hotels
- Delta Hotels by Marriott Columbia Northeast
- Forest Acres Hotels
- Cottages in South Carolina
- Pet-Friendly Hotels in Columbia
- Flights to Columbia
- Flights from Elgin
- Flights from Columbia Metropolitan
- Flights from Halifax (YHZ) to Columbia (CAE)
- Flights from Ottawa (YOW) to Columbia (CAE)
- Flights from Columbia
- Flights from Edmonton (YEG) to Columbia (CAE)
- Flights from Vancouver (YVR) to Columbia (CAE)
- Flights to South Carolina
- Flights from Toronto (YYZ) to Columbia (CAE)
- Flights from South Carolina
- Flights to Blythewood
- Flights from Calgary (YYC) to Columbia (CAE)
- Golf Vacation Packages South Carolina
- Visit Lake Carolina
- Beach Vacation Packages South Carolina
- Golf Vacation Packages South Carolina Midlands
- South Carolina Vacations
- Allen University
- Visit South Carolina
- Denmark Vacations
- Congaree National Park
- Columbia Vacations
- Visit Downtown Columbia
- All inclusive Vacation Packages South Carolina
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
