South Carolina Midlands Vacation Packages

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Your South Carolina Midlands Vacation

Whether you're heading to South Carolina Midlands for its rich history, spectacular views or something else entirely, this destination is one you won't forget in a hurry. Create your ultimate break with one of our South Carolina Midlands vacation packages. With so much to see and do on a trip to South Carolina Midlands, it can be difficult to know where to start. Kick off your travels in Columbia at Riverbanks Zoo and Garden and Williams Brice Stadium — two popular attractions here. Another city worthy of a spot on your itinerary is Florence. Don't miss Magnolia Mall and Mcleod Regional Medical Centre. Expedia has flights, hotels, car rentals and more to help you create your very own customized South Carolina Midlands vacation today.

Top South Carolina Midlands Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Sands Ocean Club Resort
Westgate Myrtle Beach Oceanfront Resort
Grand Atlantic Ocean Resort
Hilton Grand Vacations Club Anderson Ocean Myrtle Beach
The Ellie Beach Resort Myrtle Beach, Tapestry By Hilton

Where to stay in South Carolina Midlands

Find the best South Carolina Midlands areas and neighborhoods for the activities you enjoy most. Learn more about South Carolina Midlands

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South Carolina Midlands Hotel Deals

Hilton Garden Inn Columbia/Harbison

Hilton Garden Inn Columbia/Harbison

3 out of 5
434 Columbiana Dr Columbia SC
Fully refundableReserve now, pay when you stay
The price is CA $123 per night from Mar 1 to Mar 2
CA $123
CA $137 total
Mar 1 - Mar 2
includes taxes & fees
8.8/10 Excellent! (1,959 reviews)
The room was very well stocked and with everything i needed very clean the service was friendly and efficient great hotel to be .

Reviewed on Feb 4, 2026

Hilton Garden Inn Columbia/Harbison
La Quinta Inn by Wyndham Columbia SE / Fort Jackson

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

3 out of 5
7333 Garners Ferry Rd Columbia SC
Fully refundableReserve now, pay when you stay
The price is CA $105 per night from Mar 8 to Mar 9
CA $105
CA $120 total
Mar 8 - Mar 9
includes taxes & fees
7.6/10 Good! (1,015 reviews)
Great room

Reviewed on Feb 2, 2026

La Quinta Inn by Wyndham Columbia SE / Fort Jackson
Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG

Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG

2.5 out of 5
211 Lanneau Ct Columbia SC
Fully refundable
The price is CA $127 per night from Feb 15 to Feb 16
CA $127
CA $141 total
Feb 15 - Feb 16
includes taxes & fees
8.8/10 Excellent! (1,028 reviews)
As always great breakfast

Reviewed on Feb 7, 2026

Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in South Carolina Midlands

What to do in South Carolina Midlands

Frequently asked questions

Can I cancel my flight booking to South Carolina Midlands due to COVID-19?
Many airlines now provide more flexibility due to COVID-19. Our Customer Service Portal will help you answer most queries about which policies apply to your South Carolina Midlands flight. It's also a good idea to check the terms and conditions of your chosen carrier — preferably before you make a booking!
What's the best way to find cheap flights to South Carolina Midlands that have flexible change policies?
It's quick and easy with Expedia. Step 1: Enter your preferred dates and destination and hit "Search." Step 2: Check "No change fee" below the "Flexible change policies" subheading on the left-hand side of your screen. Step 3. Snag a cheap and flexible ticket to South Carolina Midlands.
What are some of the general tips for travelers to South Carolina Midlands during the COVID-19 outbreak?
COVID-19 may have changed how we travel, but it hasn't shut down our lust for exploring. Here are some tips on how to cope with the new challenges of traveling:
  • Understand what rules and restrictions apply to both your origin and destination. You may not be able to travel depending on local circumstances, so don't forget to check before you book your flight.
  • Wear a face mask during airport screening. A TSA employee will require you to temporarily lower your mask to verify your identity.
  • Instead of handing a TSA agent your boarding pass, position it directly on the scanner yourself. After that, hold it up for inspection.
  • One container of liquid hand sanitizer is now permitted in your carry-on luggage. It must be no bigger than 12 oz (350 ml), and you'll need to remove it from your bag for screening.
  • To minimize handling during screening, place personal items such as your phone and loose change into your carry-on instead of the bins.
  • Transport any food items in a clear plastic bag and also place them in a screening bin. Keeping your food separate from your carry-on makes it less likely that a TSA employee will need to open your bag for inspection.

Which airlines fly to South Carolina Midlands?
Lock in your airfare with Delta and then begin planning your South Carolina Midlands itinerary. This top carrier offers 221 flights per month to Columbia Metropolitan Airport (CAE), a central gateway.
How can I find cheap tickets to South Carolina Midlands?
In the last seven days, was the lowest price for a flight to South Carolina Midlands. If you'd love to save even more, book in advance and be flexible with your dates. Search for your airfare to South Carolina Midlands, then see prices for nearby days by clicking on the "flexible dates" link above.
How much is a flight to South Carolina Midlands?
If you were flying one way from (), you could've snapped up a low-cost fare for just in the last seven days. Round-trip journeys to South Carolina Midlands ranged from to over the same period.
What are the most popular airports to fly into in South Carolina Midlands?
Start organizing your South Carolina Midlands getaway by booking one of the 742 flights a month to Columbia Metropolitan Airport (CAE). This is the region's main entryway.
When is the cheapest time to fly to South Carolina Midlands?
If you're not fixed on what date you jet off to South Carolina Midlands, try to leave early on in the week. The most economical day to take off is generally Tuesday, closely followed by Monday. Saturday is typically the most expensive day, with many vacationers preferring to take off on the weekend.
How much is a plane ticket to South Carolina Midlands?
In the last seven days, plane fares to South Carolina Midlands varied between and . Prices usually rise as your travel date nears, so land yourself a bargain today.
Which airlines with flights to South Carolina Midlands employ COVID-19 cleanliness policies?
To help limit contact between passengers and flight crew during the COVID-19 outbreak, airlines have taken physical distancing and other protective measures to the skies. A great example of these are:
  • American Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.
  • Delta - this airline is known for electrostatic cleaning and cleaning with disinfectant.
  • United Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.